Uploaded by · Ralph Gräf [+]

Figure legend

FIGURE 3 A nucleus in mitotic prophase, with chromosomes (ch) and kinetochores (k). The spb has a diameter of about 250 nm in the plane of section and it appears in three consecutive sections so that the diameter perpendicular to the plane of section is also about 250 nm. Its thickness is 110 nm and it appears to be composed of two disks stacked on top of each other (b). The dense particles have been replaced by a dense halo which surrounds the spb and from which microtubules extend. Fig. 3 a-d is taken from consecutive serial sections. (a) Bar is 500 nm. x 30,000. (b) to (d) Bar is 100 nm. x 90,000. Fig. 3a gives an overview over the NAB positioning in the cell.

Figure notes

Fig. 3b clearly shows that the core structure consists of three major layers. Today we prefer to call the NAB a centrosome, since it appears to serve all its functions and contains many conserved centrosomal components.

Image details

Image summary

  • Species · Dictyostelium discoideum
  • Reference · Moens PB, J Cell Biol 68(1), 1976 · Pubmed · CrossRef
  • Submitted by · Ralph Gräf on 07/20/2010.
  • Published by · Zita Santos on 02/03/2011.

Image annotation

  • Centrosome
    • Nucleous Associated Body
      • Number of NABs

        1
      • Number of layers

        3
      • Shape

        Globular
        Disc
      • Position in the cell

        Anchored at the nuclear membrane
        Tight connection to nucleus
        At the spindle poles
      • Associated with

        Chromatin

Image extra structures

  • Extra structures · centromeres - golgi appartus